Lasix (Furosemide)

Description

Lasix is fast effective diuretic.

The bioavailability of the active substance is 64%, but it can be reduced by 30% depending on the disease.

Indications for use

Lasix is used in case of:

  • Edema  syndrome, which appeared due to cardiac, hepatic, renal diseases and intoxication.
  • Pulmonary edema and brain edema.
  • Swelling resulting from a burn disease.
  • Hypertension.
  • Forced diuresis.
  • Renal failure.
  • Preeclampsia in pregnant women.

Method of application

Dosage and method of application are prescribed by the attending physician for each patient individually. The dose during the course should be adjusted depending on the magnitude of diuresis and severity of the disease.

Indications for use of Lasix

The drug can be prescribed in pill form or intravenously with minimal dose. Before the course you need to check the pressure, electrolyte balance and acid-base indicators.

During the course the loss of electrolytes should be monitored and constantly replenished. The substance is excreted with urine.

Most often doctors prescribe pills, however, if the human condition is regarded as life-threatening, a doctor may appoint intravenous injections.

The solution is taken slowly, about two minutes. However, you need to take pills for improvement and stabilization of the condition: the intravenous injections may cause side effects.

Take pills inside, before meals, without chewing and drinking any liquid: water, tea, juice, juice.

In 5 minutes after injection you can notice an excellent diuretic result, the maximum of which can be fixed in half an hour, and the duration of the effective period is up to two hours.

In case of the oral way of reception, the result will appear within one hour and reach maximum in one hour and a half. In this case the effective period will last about seven hours.

The dose for children is calculated by weight. When it is taken orally, the dose can start from 2 mg per kilogram, and when it is taken by injection, the dose will be 1 mg per kilogram of body weight.

You can gradually increase the dose by 2 mg per kilogram when it is taken in tablets and 1 mg per kg when it is taken by injection. Increase the dose for children with the same intervals as for adults.

The active substance of the drug is a loop diuretic, a diuretic with severe, rapidly developing, short-lived, potent and moderate pressure drop.

Interaction with other drugs

If you are prescribed medication with corticosteroids and laxatives, you should control electrolyte composition of blood, because it increases the probability of developing of hypokalemia.

In case of therapy together with antibiotics-cephalosporins, their level in blood may increase and then you can worry about any side effects.

Diuretic effect may be reduced when administered simultaneously with probenecid, phenytoin, and NSAIDs.

The administration with IACF can lead to increased hypotensive effect and kidneys diseases.

Also, a diuretic may enhance the toxic effects of theophylline and lithium drugs.

Side effects

If the drug is taken in large amounts, it may gradually decrease the volume of circulating blood; in result it can develop clots and cause thrombosis.

It can cause fluid and electrolyte fluctuations: changes in biochemistry: increase the amount of creatinine, cholesterol, glucose Ave.

As for the cardiovascular system you may observe a quick decrease in blood pressure, which will manifest common symptoms.

Allergic reactions can manifest in skin disorders: purpura, urticaria, dermatitis, itching, etc. It may rarely cause pathology of the blood: eosinophilia, leukopenia, etc.

In case of overdose you can fix the pressure drop and disturbance of the electrolytic balance.

Drug contraindications

It is impossible to apply the medicine in disorders of the electrolytic balance, intolerance to furosemide or any other part, with anuria, dehydration, and liver coma, hypokalemia, and hyponatremia.

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